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The correct choice indicates that Prescription Drug Plans (PDPs) can enhance coverage for both Original Medicare and some Medicare Advantage plans. This is significant because Original Medicare does not include prescription drug coverage on its own, thereby allowing PDPs to fill this gap for those who require medication coverage.

In the case of Medicare Advantage plans, while many of these plans provide integrated drug coverage, there are specific Medicare Advantage options available that do not offer prescription drug coverage. PDPs provide a means for beneficiaries of those plans to access necessary medications as well, ensuring they have the flexibility to manage their health needs effectively.

This comprehensive approach is crucial for understanding Medicare's structure, where different components work in tandem to provide beneficiaries with an array of healthcare services, including those that involve prescription drugs. The ability of PDPs to add coverage provides beneficial options for individuals navigating Medicare’s various plans to secure necessary prescriptions.